GLOBAL ORGAN ON A CHIP MARKET FORECAST 2019-2027

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GLOBAL ORGAN ON A CHIP MARKET FORECAST 2019-2027

The global Organ-on-a-Chip market is anticipated to grow at a CAGR of 39.70% between 2019 and 2027 and anticipated to generate revenue of $230.2 million by 2027. An organ-on-chip is also known as multi-channel 3D microfluidic cell culture chip. It is a type of artificial organ that stimulates mechanics, activities, and physiological response of whole organs and organ structures.

GLOBAL ORGAN ON A CHIP MARKET FORECAST 2019-2027

Global Organ on a Chip Market by Organ Type (Liver, Heart, Lung, Other Organ Type) by Application (Drug Discovery, Toxicology Research, Other Application) by End-user (Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Other End-user) by Geography.

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The global Organ-on-a-Chip market is anticipated to grow at a CAGR of 39.70% between 2019 to 2027 and anticipated to generate revenue of $230.2 million by 2027. An organ-on-chip is also known as multi-channel 3D microfluidic cell culture chip. It is a type of artificial organ that stimulates mechanics, activities, and physiological response of whole organs and organ structures. The Organ-on-a-Chip market is primarily driven by the following factors:

  • The rise in the demand for early recognition of drug toxicity
  • Technological advancements
  • Growing usages of Organs-on-Chips for animal testing

The important drivers that are increasing the growth of the global Organ-on-a-Chip market have been the rise in the demand for early recognition of drug toxicity and technological advancements. The significant rise in the demand for early recognition of drug toxicity is expected to drive the growth of the organs-on-chips market. The Organ-on-a-Chip market has gathered many players from different horizons, and it is evolving continuously due to rapid technological advances and the field’s strong multidisciplinary attractiveness.

The application and organ type of the market are used extensively for various purposes. Organ-on-a-Chip has the potential to serve as a new enabling platform for validation and identification of safety, efficacy, and sturdiness of possible targets timely in the pipeline for increasing the chances of success in clinical trials. Liver-on-a-chip models are used to identify metabolites generated from compound breakdown and investigate their potential secondary toxic effects. Liver chip models utilize the minimal cells and reagents, allowing more tests to be performed using human cells of the limited quantity.

The Organ-on-a-Chip technology was proposed to mimic the dynamic conditions of the cardiovascular system, in particular, heart and general vasculature. The lung-on-a-chip technology is a complex, three-dimensional model of a living, breathing human lung on a microchip. The applications of the gut-on-a-chip system are still at the early stages of development, and they hold great promise for studying the interactions between the host and the microbiome. These initial models of gut-on-a-chip were amended from the developments in lung-on-a-chip that allowed microfluidic systems to model the recurring breathing gestures of the human lung efficiently.

The technical hitches associated with Organs-On-Chips technology is the major factor that is hindering the market advancement. The major challenge in Organ-on-a-Chip technology is reproducing the architectural complexity of the human tissues and organs by in vitro technique in a miniaturized fashion and arranging them in the interconnected systems to recapitulate the human tissue/organ interactions. The complexity and such drawbacks of the organs-on-chips technology are expected to obstruct the growth of the market

The Global Organ-on-a-Chip market segments include organ type, application, and end-user.

Organ type is sub-segmented into:

  • Liver
  • Heart
  • Lung
  • Other organ type

Application is sub-segmented into:

  • Drug discovery
  • Toxicology research
  • Other application

End-user is sub-segmented into:

  • Pharmaceutical and biotechnology companies
  • Academic and research institutes
  • Other end-user

This report covers the present market conditions and the growth prospects of the global Organ-on-a-Chip market for 2019-2027 and considered the revenue generated through the sales of Organ-on-a-Chip for organ type, application, and end-user to calculate the market size by considering 2018 as the base year.

Geographically, the global Organ-on-a-Chip market has been segmented on the basis of four major regions, which are:

  • North America: The United States & Canada
  • Asia-Pacific: China, India, Japan, Australia, South Korea & Rest of APAC
  • Europe: The United Kingdom, France, Germany, Italy, Spain & Rest of Europe
  • Rest of World: Latin America & Middle East and Africa

The Organ-on-a-Chip market in North America is expected to hold the largest share by 2027 because of the possibilities of a surge in the adoption of organs-on-chips over 2D and 3D cell cultures. North America Organ-on-a-Chip market constitutes approximately 49% market share. The independent agency of the United States federal government, NASA had been preparing to send devices containing the human cells in a 3D matrix acknowledged as organs-on-chips or tissue chips to the International Space Station (ISS) to test how they would respond to stress, drugs, and genetic changes.

On the other hand, the Asia-Pacific market is anticipated to the fastest-growing region for the Organ-on-a-Chip market. The rise in disposable income of the population is expected to increase the adoption of Organ-on-a-Chip technology in this region, thereby fueling market growth. Growing government funding for regenerative medicines in research institutes along with the growing number of clinical trials based on cell-based therapy and investment in R&D activities is expected to supplement the growth of the Organ-on-a-Chip market in the Asia-Pacific region during the forecast period.

The Organ-on-a-Chip market is segmented on end-user, which is sub-divided into Pharmaceutical and biotechnology companies, academic and research institutes and others. Increasing R&D investment in the pharmaceutical sector across the globe will be boosting the Organ-on-a-Chip market while accelerating R&D activities are enhancing drug discovery and development. Research centers are among the foremost end-users of Organ-on-a-Chip, especially in the field of Life Sciences research. Increasing spending on research and growing funding for cancer research are subsequently propelling the growth of the Organ-on-a-Chip market across the world. Contract research organizations are specialized outsourcing research teams with core capabilities in fields such as cell line studies, toxicology, immunology, and pre-clinical services.

The major market players of the global Organ-on-a-Chip market are:

  • Organovo Holdings, Inc.
  • Emulate, Inc.
  • Hurel Corporation
  • Insphero AG
  • MIMETAS BV

Company profiles cover the analysis of important market players. Organovo Holdings, Inc. is a biotechnology company that develops bio printed humanoid tissues grounded on its 3D human tissue technology that emulate human diseases and biology. MIMETAS BV is involved in the development of novel hardware, biological models and assays. The company has its main manufacturing facility in Enschede. The main product in its product portfolio is OrganoPlates.

Key findings of the global Organ-on-a-Chip market:

  • Lung on-chip organ type holds the largest market share
  • Drug discovery is the fastest growing application
  • Pharmaceutical and biotechnology companies are the major end-user of the Organ-on-a-Chip technology
  1. RESEARCH SCOPE
    • STUDY GOALS
    • SCOPE OF THE MARKET STUDY
    • WHO WILL FIND THIS REPORT USEFUL?
    • STUDY AND FORECASTING YEARS
  2. RESEARCH METHODOLOGY
    • SOURCES OF DATA
      • SECONDARY DATA
      • PRIMARY DATA
    • TOP-DOWN APPROACH
    • BOTTOM-UP APPROACH
    • DATA TRIANGULATION
  3. EXECUTIVE SUMMARY
    • MARKET SUMMARY
    • KEY FINDINGS
      • LUNG ON CHIP ORGAN TYPE HOLDS THE LARGEST MARKET SHARE
      • DRUG DISCOVERY IS THE FASTEST GROWING APPLICATION
      • PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES ARE THE MAJOR END-USER OF THE ORGAN ON A CHIP TECHNOLOGY
  1. MARKET DYNAMICS
    • MARKET SCOPE & DEFINITION
    • MARKET DRIVERS
      • RISE IN THE DEMAND FOR EARLY DETECTION OF DRUG TOXICITY
      • TECHNOLOGICAL ADVANCEMENTS
      • GROWING USAGES OF ORGANS-ON CHIPS FOR ANIMAL TESTING
    • MARKET RESTRAINTS
      • DIFFICULTIES ASSOCIATED WITH THE ORGANS-ON-CHIPS TECHNOLOGY
    • MARKET OPPORTUNITIES
      • INCREASING R&D ACTIVITIES
      • GROWING OPPORTUNITIES IN DRUG DEVELOPMENT
    • MARKET CHALLENGES
      • HIGH COST ASSOCIATED WITH THE ORGAN ON A CHIP DEVICES
      • SHORTAGE OF SKILLED PERSONAL
  1. MARKET BY ORGAN TYPE
    • LIVER
    • HEART
    • LUNG
    • OTHER ORGAN TYPE
  2. MARKET BY APPLICATION
    • DRUG DISCOVERY
    • TOXICOLOGY RESEARCH
    • OTHER APPLICATION
  3. MARKET BY END-USER
    • PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES
    • ACADEMIC AND RESEARCH INSTITUTES
    • OTHER END-USER
  4. KEY ANALYTICS
    • PORTER’S FIVE FORCES MODEL
      • THREAT OF NEW ENTRANTS
      • THREAT OF SUBSTITUTE
      • BARGAINING POWER OF BUYERS
      • BARGAINING POWER OF SUPPLIERS
      • THREAT OF COMPETITIVE RIVALRY
    • ORGAN ON A CHIP MARKET POTENTIAL
    • REGULATORY FRAMEWORK
    • INVESTMENT ANALYSIS
    • SUPPLY CHAIN ANALYSIS
      • RAW MATERIAL SUPPLIERS
      • MANUFACTURERS
      • DISTRIBUTORS
      • END-USERS
    • OPPORTUNITY MATRIX
  5. GEOGRAPHICAL ANALYSIS
    • NORTH AMERICA
      • THE UNITED STATES
      • CANADA
    • EUROPE
      • FRANCE
      • GERMANY
      • THE UNITED KINGDOM
      • ITALY
      • SPAIN
      • REST OF EUROPE
    • ASIA PACIFIC
      • JAPAN
      • CHINA
      • INDIA
      • AUSTRALIA
      • SOUTH KOREA
      • REST OF ASIA PACIFIC
    • REST OF WORLD
      • LATIN AMERICA
      • MIDDLE EAST AND AFRICA
  1. COMPETITIVE LANDSCAPE
    • MARKET POSITION ANALYSIS
    • COMPANY PROFILES
      • AXOSIM INC.
      • BEONCHIP
      • BIOMIMX SRL
      • CN INNOVATIONS HOLDINGS LIMITED (CN BIO INNOVATIONS)
      • ELVEFLOW
      • EMULATE
      • FLUIGENT
      • HESPEROS
      • HUREL CORPORATION
      • INSPHERO AG
      • MIMETAS B.V.
      • NORTIS INC.
      • ORGANOVO HOLDINGS, INC.
      • SYNVIVO
      • TARA BIOSYSTEMS, INC.
      • TISSUSE GMBH

 

LIST OF TABLES

TABLE 1        GLOBAL ORGAN ON A CHIP MARKET BY REGION 2019-2027 ($ THOUSAND)

TABLE 2        GLOBAL ORGAN ON A CHIP MARKET BY ORGAN TYPE 2019-2027 ($ THOUSAND)

TABLE 3        GLOBAL ORGAN ON A CHIP MARKET BY APPLICATION 2019-2027 ($ THOUSAND)

TABLE 4        GLOBAL ORGAN ON A CHIP MARKET BY END-USER 2019-2027 ($ THOUSAND)

TABLE 5        TIME REQUIRED IN THE DRUG DEVELOPMENT PROCESS

TABLE 6        RAW MATERIAL SUPPLIERS

TABLE 7        MANUFACTURERS OPERATING IN THE ORGAN ON A CHIP MARKET

TABLE 8        END-USER OF THE ORGAN ON A CHIP MARKET

TABLE 9        GLOBAL ORGAN ON A CHIP MARKET BY REGION 2019-2027 ($ THOUSAND)

TABLE 10      NORTH AMERICA ORGAN ON A CHIP MARKET BY COUNTRY 2019-2027 ($ THOUSAND)

TABLE 11      EUROPE ORGAN ON A CHIP MARKET BY COUNTRY 2019-2027 ($ THOUSAND)

TABLE 12      ASIA PACIFIC ORGAN ON A CHIP MARKET BY COUNTRY 2019-2027 ($ THOUSAND)

TABLE 13      REST OF WORLD ORGAN ON A CHIP MARKET BY REGION 2019-2027 ($ THOUSAND)

TABLE 14      ORGAN ON A CHIP COMPANY MARKET POSITION ANALYSIS 2018

 

LIST OF FIGURES

FIGURE 1      GLOBAL ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 2      R&D PROJECTS IN THE PIPELINE OF TOP 20 COMPANIES, 2018

FIGURE 3      GLOBAL ORGAN ON A CHIP MARKET SHARE BY ORGAN TYPE 2018 & 2027 (%)

FIGURE 4      GLOBAL ORGAN ON A CHIP MARKET BY LIVER 2019-2027 ($ THOUSAND)

FIGURE 5      GLOBAL ORGAN ON A CHIP MARKET BY HEART 2019-2027 ($ THOUSAND)

FIGURE 6      GLOBAL ORGAN ON A CHIP MARKET BY LUNG 2019-2027 ($ THOUSAND)

FIGURE 7      GLOBAL ORGAN ON A CHIP MARKET BY OTHER ORGAN TYPE 2019-2027 ($ THOUSAND)

FIGURE 8      GLOBAL ORGAN ON A CHIP MARKET SHARE BY APPLICATION 2018 & 2027 (%)

FIGURE 9      GLOBAL ORGAN ON A CHIP MARKET BY DRUG DISCOVERY 2019-2027 ($ THOUSAND)

FIGURE 10   GLOBAL ORGAN ON A CHIP MARKET BY TOXICOLOGY RESEARCH 2019-2027 ($ THOUSAND)

FIGURE 11   GLOBAL ORGAN ON A CHIP MARKET BY OTHER APPLICATION 2019-2027 ($ THOUSAND)

FIGURE 12   GLOBAL ORGAN ON A CHIP MARKET SHARE BY END-USER 2018 & 2027 (%)

FIGURE 13   GLOBAL ORGAN ON A CHIP MARKET BY PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES 2019-2027 ($ THOUSAND)

FIGURE 14   GLOBAL ORGAN ON A CHIP MARKET BY ACADEMIC AND RESEARCH INSTITUTES 2019-2027 ($ THOUSAND)

FIGURE 15   GLOBAL ORGAN ON A CHIP MARKET BY OTHER END-USER 2019-2027 ($ THOUSAND)

FIGURE 16   PORTER’S FIVE FORCE MODEL

FIGURE 17   DRUG DEVELOPMENT PROCESS

FIGURE 18   PHASES OF DRUG DISCOVERY

FIGURE 19   SUPPLY CHAIN ANALYSIS OF ORGAN ON A CHIP MARKET

FIGURE 20   GLOBAL ORGAN ON A CHIP MARKET REGIONAL OUTLOOK 2018 & 2027 (%)

FIGURE 21   THE UNITED STATES ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 22   CANADA ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 23   FRANCE ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 24   GERMANY ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 25   THE UNITED KINGDOM ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 26   ITALY ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 27   SPAIN ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 28   REST OF EUROPE ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 29   JAPAN ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 30   CHINA ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 31   INDIA ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 32   AUSTRALIA ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 33   SOUTH KOREA ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 34   REST OF ASIA PACIFIC ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 35   LATIN AMERICA ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

FIGURE 36   MIDDLE EAST AND AFRICA ORGAN ON A CHIP MARKET 2019-2027 ($ THOUSAND)

  1. MARKET BY ORGAN TYPE
    • LIVER
    • HEART
    • LUNG
    • OTHER ORGAN TYPE
  2. MARKET BY APPLICATION
    • DRUG DISCOVERY
    • TOXICOLOGY RESEARCH
    • OTHER APPLICATION
  3. MARKET BY END-USER
    • PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES
    • ACADEMIC AND RESEARCH INSTITUTES
    • OTHER END-USER
  4. GEOGRAPHICAL ANALYSIS
    • NORTH AMERICA
      • THE UNITED STATES
      • CANADA
    • EUROPE
      • FRANCE
      • GERMANY
      • THE UNITED KINGDOM
      • ITALY
      • SPAIN
      • REST OF EUROPE
    • ASIA PACIFIC
      • JAPAN
      • CHINA
      • INDIA
      • AUSTRALIA
      • SOUTH KOREA
      • REST OF ASIA PACIFIC
    • REST OF WORLD
      • LATIN AMERICA
      • MIDDLE EAST AND AFRICA

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