GLOBAL INFERTILITY TESTING AND TREATMENT MARKET FORECAST 2019-2027

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GLOBAL INFERTILITY TESTING AND TREATMENT MARKET FORECAST 2019-2027

Global infertility testing and treatment market are estimated to grow with approx. 6.39% CAGR during the year 2019-2027. The base year considered for the study is 2018 and the forecast period is 2019-2027. Global infertility testing and treatment market are primarily driven by the following factors: The rise in infertility and treatment awareness

GLOBAL INFERTILITY TESTING AND TREATMENT MARKET FORECAST 2019-2027

Global Infertility Testing and Treatment Market by Male Infertility Testing and Treatment (Male Infertility Testing (Dna Fragmentation, Oxidative Stress Analysis, Sperm Penetration Assay, Computer Assisted Semen, Analysis (Casa), Sperm Agglutination, Microscopic Examination, Others) Male Infertility Treatment (Vasovasostomy and Vasoepididymostomy (Vasectomy Reversal), Sperm Retrieval Treatment, Microsurgical Sperm Aspiration (Mesa), Testicular Sperm Extraction (Tese), Varicocele Repairs, Assisted Reproductive Techniques (Art), Intrauterine Insemination (Iui), in Vitro Fertilization (Ivf), Intracytoplasmic Sperm Injection (Icsi))) by Female Infertility Testing and Treatment (Female Infertility Testing (Ovulation Testing, Hysterosalpingography, Laparoscopy, Transvaginal Ultrasound, Ovarian Reserve Testing, Hormonal Level Testing, Others (Genetic Testing)) Female Infertility Treatment (in Vitro Fertilization, Intrauterine Insemination (Iui), Drug and Hormone Therapies)) by End-users (Fertility and Surgical Centers, Hospitals and Research Laboratories, Cryobanks) by Geography.

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Global infertility testing and treatment market are estimated to grow with approx. 6.39% CAGR during the year 2019-2027. The base year considered for the study is 2018 and the forecast period is 2019-2027. Global infertility testing and treatment market are primarily driven by the following factors:

  • The rise in infertility and treatment awareness
  • Medical tourism for fertility treatments
  • Surrogacy laws are getting more defined
  • Healthcare advances have fine-tuned fertility treatment
  • Increasing effectiveness of treatments
  • Healthier donor eggs
  • Introduction of new testing devices

The important driver increasing growth in the global Infertility testing and treatment market are a rise in infertility and treatment awareness and the introduction of new testing devices. According to US Census Bureau Statistics 2014, 142.9 million people were found to be infertile. According to the World Health Organization, one in every six couple suffers from infertility related issues.

Infertility is caused by various reasons such as physiological dysfunction, anatomical or genetic disorder, STD (sexually transmitted diseases), endocrinological and immunological problems. Malaria, gonorrhea, chlamydia (STI) and other existing diseases may also cause infertility.

Physiological causes that may cause infertility are a tubal blockage, congenital malformation, abnormal ovulation, low quality and quantity of sperm and ejaculatory dysfunctions. Additionally, infection, higher age, pollution, and other environmental hazards may lead to infertility. The fertility rate has been decreasing over the years with a rising rate of infertility throughout the world.

Female infertility treatment market is expected to lead the global infertility market. In 2016, In Vitro Fertilization (IVF) market held the largest share of the female infertility treatment. Low quality, quantity, and motility of sperms in male and hostile environment for sperms in the female uterus may lead to infertility. The infertile male and female couples adopt in vitro fertilization to combine egg and sperm in the laboratory, and the fertilized embryo is then placed into the uterus.

IVF technique is mostly recommended along with ICSI technique for men with infertility problems. ICSI is the latest technology in in-vitro fertilization where a quality sperm is directly fertilized with the female egg, and the embryo is placed into the female uterus. Drug and hormone therapies are the second largest growing segment of the female infertility treatment market.

The required treatment procedures are still out of reach for many because of the high costs involved and country-wise regulatory issues are the major factors hindering the Infertility testing and treatment market. The high cost of IVF procedures is one of the biggest restraints, and the treatment is still beyond the reach of numerous infertile couples.

The cost is dependent upon the type of treatment and the age of the woman seeking the treatment. The amount to be paid by a 35 years old or younger woman will be less, and the investment increases as the age of the woman increases. Markets in India and the Czech Republic have seen an upsurge in the number of IVF clinics due to an increase in reproductive tourism.

In the African subcontinent, where the rate of secondary infertility is very high, IVF is unaffordable for the local population. IVF is costliest in the US. It becomes even more expensive for the locals when coupled with egg donation.

The global infertility testing and treatment market segments include market by gender and end-user.

Male infertility market is sub-segmented into:

  • Testing
  • Treatment

Female infertility market is sub-segmented into:

  • Testing
  • Treatment

End-users market is sub-segmented into:

  • Fertility and Surgical Centers
  • Hospitals and Research Laboratories
  • Cryobanks

The report scope is widely categorized on the basis of its components which includes male and female treatment and types. Moreover, the market revenue estimates and forecast includes only infertility testing and treatment systems and exclude conventional treatment methods.

Geographically, the global Infertility testing and treatment market have been segmented on the basis of four major regions, which includes:

Europe is anticipated to account the largest market share during 2019-2027 as the majority of the world’s IVF clinics are in Europe. The average cost of IVF in the European region is about $4,500; it is this factor that attracts the patients dealing with infertility from all over the world. Companies are also investing in the European region.

Recently, Genea Biomedx opened its facility in Europe. The Czech Republic has become a popular destination for couples seeking infertility treatment at lower prices. Approximately, over 30 clinics are known to offer a variety of services for infertility. The clinics in the Czech Republic are well regulated, and success rates are comparable with Spain for egg donation.

On the other hand, the Asia-Pacific market is anticipated to be the fastest-growing region for the infertility testing and treatment market. A major driver for the increasing demand for infertility treatments is lowering birth rate in some major Asian countries such as Japan, South Korea, Singapore, and Taiwan. The current birth rate in these countries is 1.5 babies per woman. The government in developed countries of the region such as Singapore and South Korea are offering to subsidize the cost of IVF treatment.

The infertility testing and treatment market is segmented based on gender which is sub-divided into male and female infertility testing and treatment. Male infertility testing includes DNA fragmentation, Oxidative stress analysis, Sperm penetration assay, Computer-Assisted Semen Analysis (CASA), Sperm agglutination, Microscopic examination, and others.

Female infertility testing market includes ovulation testing, hysterosalpingography, laparoscopy, transvaginal ultrasound, ovarian reserve testing, hormonal level testing, and others. Female infertility treatment market is further segmented into IVF, IUI, and drug and hormone therapies. The end-users market is segmented into fertility and surgical centers, hospitals and research laboratories, and cryobanks.

The major market players of the global Infertility testing and treatment market are:

  • Endo Pharmaceuticals
  • Ferring Pharmaceuticals
  • Halotech DNA
  • Merck
  • Thermo Fisher Scientific Inc.
  • Other companies

Company profiles covers analysis of important players. These companies are using organic and inorganic strategies for growth. For instance, in April 2017, Merck, through its ‘Merck More than a Mother’ initiative in partnership with Asia Pacific Initiative on Reproduction (ASPIRE), has conducted a panel to address challenges and solutions to improve access to regulated fertility care in Africa and Asia.

In December 2016, Ferring Pharmaceuticals and MetaboGen AB announced a multi-year research collaboration aimed at developing a microbiome-based product to prevent and treat intrahepatic cholestasis of pregnancy (ICP), a potentially serious liver disorder which affects around 400,000 pregnant women annually.

Key Findings of the global infertility testing and treatment market:

  • The rise in infertility and treatment awareness and the introduction of new testing devices is fueling growth in global infertility testing and treatment market
  • Europe is anticipated to account for the largest revenue share in 2018
  • Female infertility treatment segment is the dominating market due to the increasing number of couples opting for IVF
  • Increasing government support
  • Product launch is the key strategy adopted by the various market players of global Infertility testing and treatment market
  • Microscopic examination segment is the major segment of male infertility testing market.
  1. RESEARCH SCOPE
    • STUDY GOALS
    • SCOPE OF THE MARKET STUDY
    • WHO WILL FIND THIS REPORT USEFUL?
    • STUDY AND FORECASTING YEARS
  2. RESEARCH METHODOLOGY
    • SOURCES OF DATA
      • SECONDARY DATA
      • PRIMARY DATA
    • TOP-DOWN APPROACH
    • BOTTOM-UP APPROACH
    • DATA TRIANGULATION
  3. EXECUTIVE SUMMARY
    • MARKET SUMMARY
    • KEY FINDINGS
      • EUROPE IS THE LARGEST MARKET
      • ASIA PACIFIC IS THE FASTEST GROWING REGION IN THE INFERTILITY MARKET
      • IVF DOMINATES THE FEMALE TREATMENT MARKET
      • OXIDATIVE STRESS ANALYSIS IS THE FASTEST GROWING MALE INFERTILITY TESTING MARKET
  1. MARKET OVERVIEW
    • MARKET DEFINITION
    • MARKET DRIVERS AND IMPACT
      • RISE IN INFERTILITY AND TREATMENT AWARENESS
      • MEDICAL TOURISM FOR FERTILITY TREATMENTS
      • SURROGACY LAWS ARE GETTING MORE DEFINED
      • HEALTHCARE ADVANCES HAVE FINETUNED FERTILITY TREATMENT
      • INCREASING EFFECTIVENESS OF TREATMENTS
      • HEALTHIER DONOR EGGS
      • INTRODUCTION OF NEW TESTING DEVICES
    • MARKET RESTRAINTS AND IMPACT
      • TREATMENT PROCEDURE OUT OF REACH TO MANY DUE TO COSTS INVOLVED
      • COUNTRY-WISE REGULATORY ISSUES
    • MARKET OPPORTUNITIES
      • REDUCING THE COST OF TREATMENT TO MAKE IT MORE ACCESSIBLE
      • IVF ATTRACTING INVESTMENTS FROM PRIVATE EQUITY INVESTORS
      • DIY TESTING INCREASING ACCESS AND REDUCING COST
    • MARKET CHALLENGES
      • INFERTILITY CONSIDERED A SOCIAL TABOO AMONGST MEN
      • PERILS OF MULTIPLE PREGNANCIES
      • TRADITIONAL TREATMENTS USED WIDELY AS AN ALTERNATIVE FOR INFERTILITY TREATMENTS
        • DIET AND SUPPLEMENTS
        • ACUPUNCTURE
        • THERAPY
        • QIGONG
  1. INFERTILITY CAUSES
    • CAUSES OF MALE INFERTILITY
      • ABNORMALITY IN THE SPERM
      • ENVIRONMENTAL FACTORS
      • POOR HEALTH AND LIFESTYLE
    • CAUSES OF FEMALE INFERTILITY
      • OVULATION DISORDERS
      • DAMAGE TO FALLOPIAN TUBES
    • MORAL QUESTIONS
  2. MALE INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)
    • MARKET BY MALE INFERTILITY TESTING
      • DNA FRAGMENTATION
      • OXIDATIVE STRESS ANALYSIS
      • SPERM PENETRATION ASSAY
      • COMPUTER ASSISTED SEMEN ANALYSIS (CASA)
      • SPERM AGGLUTINATION
      • MICROSCOPIC EXAMINATION
      • OTHERS
    • MARKET BY MALE INFERTILITY TREATMENT
      • VASOVASOSTOMY AND VASOEPIDIDYMOSTOMY (VASECTOMY REVERSAL)
      • SPERM RETRIEVAL TREATMENT
      • MICROSURGICAL SPERM ASPIRATION (MESA)
      • TESTICULAR SPERM EXTRACTION (TESE)
      • VARICOCELE REPAIRS
      • ASSISTED REPRODUCTIVE TECHNIQUES (ART)
      • INTRAUTERINE INSEMINATION (IUI)
      • IN VITRO FERTILIZATION (IVF)
      • INTRACYTOPLASMIC SPERM INJECTION (ICSI)
  1. FEMALE INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)
    • MARKET BY FEMALE INFERTILITY TESTING
      • OVULATION TESTING
      • HYSTEROSALPINGOGRAPHY
      • LAPAROSCOPY
      • TRANSVAGINAL ULTRASOUND
      • OVARIAN RESERVE TESTING
      • HORMONAL LEVEL TESTING
      • OTHERS (GENETIC TESTING)
    • MARKET BY FEMALE INFERTILITY TREATMENT
      • IN VITRO FERTILIZATION
      • INTRAUTERINE INSEMINATION (IUI)
      • DRUG AND HORMONE THERAPIES
  1. GLOBAL INFERTILITY TESTING AND TREATMENT MARKET BY END-USERS 2019-2027 ($ MILLION)
    • FERTILITY AND SURGICAL CENTERS
    • HOSPITALS AND RESEARCH LABORATORIES
    • CRYOBANKS
  2. KEY ANALYTICS
    • PORTER’S 5 FORCE MODEL
      • THREAT OF NEW ENTRANTS
      • THREAT OF SUBSTITUTE PRODUCTS
      • BARGAINING POWER OF BUYERS
      • BARGAINING POWER OF SUPPLIERS
      • INTENSITY OF COMPETITIVE RIVALRY
    • VALUE CHAIN ANALYSIS
      • RAW MATERIAL PROCUREMENT
      • MANUFACTURING
      • SUPPLY LOGISTICS
      • DISTRIBUTION CHANNELS
      • END-USERS
    • KEY BUYING CRITERIA
      • TREATMENT OPTIONS
      • QUALITY OF MEDICAL PROCEDURES
      • PRICE OF TREATMENTS
      • SHIFT TOWARDS MEDICAL TOURISM
      • REIMBURSEMENT
    • REGULATORY FRAMEWORK
    • VENDOR LANDSCAPE
    • OPPORTUNITY MATRIX
  3. GLOBAL INFERTILITY TESTING AND TREATMENT MARKET REGIONAL ANALYSIS 2019-2027 ($ MILLION)
    • NORTH AMERICA
      • US
      • CANADA
    • ASIA PACIFIC
      • CHINA
      • INDIA
      • JAPAN
      • SOUTH KOREA
      • REST OF ASIA-PACIFIC
    • EUROPE
      • UK
      • GERMANY
      • FRANCE
      • NORDICS
      • RUSSIA
    • REST OF WORLD
  4. COMPANY PROFILES
    • ANDROLOGY SOLUTIONS
    • ENDO PHARMACEUTICALS
    • PROGYNY
    • FERRING PHARMACEUTICALS
    • GENEA
    • HALOTECH DNA
    • IRVINE SCIENTIFIC
    • MERCK
    • ORIGIO
    • OVASCIENCE
    • VITROLIFE AB
    • THERMO FISHER SCIENTIFIC INC.
    • THE COOPER COMPANIES, INC.
    • QUEST DIAGNOSTIC
    • ESCO MICRO PTE. LTD.

 

LIST OF TABLES

TABLE 1 GLOBAL INFERTILITY TESTING AND TREATMENT MARKET BY GENDER 2019-2027 ($ MILLION)

TABLE 2 AVERAGE COST COMPARISON OF INFERTILITY TREATMENTS

TABLE 3 GLOBAL MALE INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

TABLE 4 GLOBAL MALE INFERTILITY TESTING MARKET 2019-2027($ MILLION)

TABLE 5 PROS AND CONS OF DNA SHARING METHODS

TABLE 6 GLOBAL DNA FRAGMENTATION MARKET BY REGION, 2019-2027 ($ MILLION)

TABLE 7 GLOBAL OXIDATIVE STRESS ANALYSIS MARKET BY REGION, 2019-2027 ($ MILLION)

TABLE 8 GLOBAL SPERM PENETRATION ASSAY MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 9 GLOBAL CASA MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 10 GLOBAL SPERM AGGLUTINATION MARKET BY REGION2019-2027 ($ MILLION)

TABLE 11 GLOBAL MICROSCOPIC EXAMINATION MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 12 GLOBAL FEMALE INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

TABLE 13 GLOBAL FEMALE INFERTILITY TESTING MARKET 2019-2027 ($ MILLION)

TABLE 14 COST OF OVULATION TESTING KITS IN THE US

TABLE 15 GLOBAL OVULATION TESTING MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 16 GLOBAL HYSTEROSALPINGOGRAPHY MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 17 GLOBAL LAPAROSCOPY MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 18 GLOBAL TRANSVAGINAL ULTRASOUND MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 19 GLOBAL OVARIAN RESERVE TESTING MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 20 GLOBAL HORMONAL LEVEL TESTING MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 21 COST OF HORMONAL TEST IN THE US

TABLE 22 GLOBAL FEMALE INFERTILITY TREATMENT MARKET 2019-2027 ($ MILLION)

TABLE 23 AVERAGE COST OF SOME INFERTILITY TREATMENTS

TABLE 24 GLOBAL IVF TREATMENT MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 25 GLOBAL IUI TREATMENT MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 26 GLOBAL DRUG AND HORMONE THERAPIES MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 27 SOME COMMON DRUG THERAPIES

TABLE 28 GLOBAL INFERTILITY TESTING AND TREATMENT MARKET BY END-USERS 2019-2027 ($ MILLION)

TABLE 29 GLOBAL FERTILITY AND SURGICAL CENTERS MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 30 GLOBAL HOSPITALS AND RESEARCH LABORATORIES MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 31 GLOBAL CRYOBANKS MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 32 GLOBAL INFERTILITY TESTING AND TREATMENT MARKET BY GEOGRAPHY 2019-2027 ($ MILLION)

TABLE 33 NORTH AMERICA INFERTILITY TESTING AND TREATMENT MARKET BY COUNTRY 2019-2027 ($ MILLION)

TABLE 34 SUCCESS OF ASSISTED REPRODUCTIVE TECHNOLOGY (ART) USING DONOR EGGS IN THE U.S. IN 2013

TABLE 35 COSTS FOR INFERTILITY TREATMENTS IN THE U.S. 2015

TABLE 36 COST OF IVF & ICSI TREATMENT, CANADA 2014

TABLE 37 ASIA-PACIFIC INFERTILITY TESTING AND TREATMENT MARKET BY COUNTRY 2019-2027 ($ MILLION)

TABLE 38 EUROPE INFERTILITY TESTING AND TREATMENT MARKET BY COUNTRY 2019-2027 ($ MILLION)

TABLE 39 COST OF IVF IN RUSSIA

LIST OF FIGURES

FIGURE 1 GLOBAL INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 2 MAJOR FERTILITY TREATMENT DESTINATION RANKING

FIGURE 3 CLINICAL ALGORITHM FOR THE EVALUATION OF INFERTILE WOMAN

FIGURE 4 RATE OF MULTIPLE DELIVERIES

FIGURE 5 CAUSES OF INFERTILITY

FIGURE 6 CAUSES OF INFERTILITY BASED ON GENDER

FIGURE 7 CAUSES OF SPERM DNA FRAGMENTATION

FIGURE 8 WORLDWIDE FALLING FERTILITY RATE (TOTAL BIRTHS PER WOMAN)

FIGURE 9 NUMBER OF IVF CYCLES PERFORMED IN THE US

FIGURE 10 US INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 11 CANADA INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 12 GROWTH IN IVF CLINICS IN ASIA

FIGURE 13 CHINA INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 14 INDIA INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 15 JAPAN INFERTILITY TESTING AND TREATMENT MARKET 2019-2027(MILLION)

FIGURE 16 SOUTH KOREA INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 (MILLION)

FIGURE 17   MEDICAL TOURISM IN SOUTH KOREA ($ MILLION)

FIGURE 18 REST OF ASIA-PACIFIC INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 19 UK INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 20 FERTILITY TREATMENT IN 2014

FIGURE 21 GERMANY INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 22 FRANCE INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 23 NORDICS INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 24 RUSSIA INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

FIGURE 25 REST OF THE WORLD INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)

  1. MALE INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)
    • MARKET BY MALE INFERTILITY TESTING
      • DNA FRAGMENTATION
      • OXIDATIVE STRESS ANALYSIS
      • SPERM PENETRATION ASSAY
      • COMPUTER ASSISTED SEMEN ANALYSIS (CASA)
      • SPERM AGGLUTINATION
      • MICROSCOPIC EXAMINATION
      • OTHERS
    • MARKET BY MALE INFERTILITY TREATMENT
      • VASOVASOSTOMY AND VASOEPIDIDYMOSTOMY (VASECTOMY REVERSAL)
      • SPERM RETRIEVAL TREATMENT
      • MICROSURGICAL SPERM ASPIRATION (MESA)
      • TESTICULAR SPERM EXTRACTION (TESE)
      • VARICOCELE REPAIRS
      • ASSISTED REPRODUCTIVE TECHNIQUES (ART)
      • INTRAUTERINE INSEMINATION (IUI)
      • IN VITRO FERTILIZATION (IVF)
      • INTRACYTOPLASMIC SPERM INJECTION (ICSI)
  1. FEMALE INFERTILITY TESTING AND TREATMENT MARKET 2019-2027 ($ MILLION)
    • MARKET BY FEMALE INFERTILITY TESTING
      • OVULATION TESTING
      • HYSTEROSALPINGOGRAPHY
      • LAPAROSCOPY
      • TRANSVAGINAL ULTRASOUND
      • OVARIAN RESERVE TESTING
      • HORMONAL LEVEL TESTING
      • OTHERS (GENETIC TESTING)
    • MARKET BY FEMALE INFERTILITY TREATMENT
      • IN VITRO FERTILIZATION
      • INTRAUTERINE INSEMINATION (IUI)
      • DRUG AND HORMONE THERAPIES
  1. GLOBAL INFERTILITY TESTING AND TREATMENT MARKET BY END-USERS 2019-2027 ($ MILLION)
    • FERTILITY AND SURGICAL CENTERS
    • HOSPITALS AND RESEARCH LABORATORIES
    • CRYOBANKS
  2. GLOBAL INFERTILITY TESTING AND TREATMENT MARKET REGIONAL ANALYSIS 2019-2027 ($ MILLION)
    • NORTH AMERICA
      • US
      • CANADA
    • ASIA PACIFIC
      • CHINA
      • INDIA
      • JAPAN
      • SOUTH KOREA
      • REST OF ASIA-PACIFIC
    • EUROPE
      • UK
      • GERMANY
      • FRANCE
      • NORDICS
      • RUSSIA
    • REST OF THE WORLD

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