GLOBAL CRISPR MARKET FORECAST 2019-2027

The global CRISPR market is anticipated to grow at a CAGR of 32.04% between 2019 and 2027. The major factor boosting the CRISPR technology market is the rising prevalence of genetic disorders. Also, the emergence of new entrants in the market is giving a certain pace to the market leading to the development of better and reliable techniques. The following factors primarily are driving the CRISPR market:

  • Increasing demand for drug discovery
  • Risk of congenital anomalies
  • Late pregnancies leading to birth disorders
  • Increasing the size of the geriatric population
  • Investment in path-breaking research technology
  • Changing lifestyles
  • Prevalence of genetic disorders
  • Increasing genetic diseases
  • Growing awareness regarding gene therapeutics

CRISPR market

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The important drivers increasing growth in the global CRISPR market are the increasing demand for drug discovery and the rising size of the geriatric population. Drug discovery technology market plays a significant role in the domain of pharmaceuticals as they are crucial for the introduction of new drugs to the market. Due to the increasing application of drugs, there is a huge opportunity in the drug discovery market for the invention of drugs for severe diseases like CVD, cancer and many more. The major influence on the pattern of healthcare spending in both developed and developing countries is the aging population in developed countries such as Western Europe, the US, etc. were the proportion of aged people that primarily utilize the healthcare services is high, due to the availability of various institutional long-term care services and medical policies.

CRISPR technology is used extensively applied for various purposes. Genome editing or genetic engineering helps in modifying an organisms genome, where deletions, insertions or replacements are carried out in the DNA of the living organism by the help of molecular machinery and engineered nucleases. Gene library refers to the gathering of cloned deoxyribonucleic acid (DNA) fragments that carry the information regarding the gene function. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) plasmids are extensively used for gene disruption and direct repair of the homologous gene. Stem cells are the basic foundation of each tissue and organ in our body. A genetically modified organism (abbreviated as GMO), is an organism in which the DNA can be altered by using genetic engineering techniques. Cell lines are a group of cells developed from a single cell and have the same genetic make-up.

Lack of awareness and the probable misappropriated use of the CRISPR gene editing tools are the major factors hindering the CRISPR market growth. This technology suffers from a serious problem in the developing countries like those of Asian and African region, where the supposed users are unaware about its huge application in several important research projects in developed nations of North America and Europe. CRISPR is related to several applications such as genome editing, genetic engineering, etc. which are considered controversial to run in the human model systems due to the ethical concerns.

The global CRISPR market is segmented into applications, products, and end users.

Applications are sub-segmented into:

  • Genome editing/ genetic engineering
  • Genetically modified organisms
  • Agricultural biotechnology
  • Others
    • GRNA database/gene library
    • CRISPR plasmid
    • Human stem cells
    • Cell line engineering

Products are sub-segmented into:

  • Design tools
  • Plasmids
  • Vectors
  • Library
  • Control kits
  • Proteins
    • Cas 9
    • Cpf1
    • Other protein
  • Genomic RNA
  • Other products

End users are sub-segmented into:

  • Industrial biotech
  • Biological research
  • Agricultural research
  • Therapeutics and drug discovery

This report covered the present market conditions and the growth prospects of the global CRISPR market for 2019-2027 and considered the revenue generated through the sales of CRISPR for products as well as an end user to calculate the market size by considering 2018 as the base year.

Geographically, the global CRISPR market has been segmented on the basis of four major regions, which include:

The CRISPR market in North America is expected to hold the largest share by 2027 due to strong possibilities of a growth trend in the biotechnology and pharmaceutical industries. In North America, the United States controls the maximum share of more than 80% in the use of CRISPR technology. The United States market is driven by the development of the pharmaceutical and biotechnology industry. The key factors that are contributing to the growth of the pharmaceuticals market in this region are increasing customer awareness along with the presence of key pharmaceuticals companies in the U.S.

On the other hand, the Asia-Pacific market is anticipated to be the fastest-growing region in the global CRISPR market. Here, Japan and China have impressive emerging economies, and the highest number of the geriatric population is also present in these two countries. A large chunk of the population of Japan and China is suffering from diabetes and other peripheral diseases, and the prevalence of these diseases is expanding at an uncontrolled pace. A large number of diabetic patients are young. Currently, in India, there are approximately sixty-four million people who are diagnosed with diabetes, among which, half of them belong to the young age category, and the rest belong to the geriatric population and children below 15 years.

The CRISPR market is segmented by end users, who are further sub-divided into biological research, agricultural biotech, industrial biotech & therapeutics, and drug discovery. Upon segmentation on the basis of products, the market is sub-segmented into designing tools, library, control kits, plasmids, vectors, proteins, gRNA, and other products. CRISPR technology has paved the way to characterize and analyze the root cause of various chronic disorders and provide gene therapy procedures for the treatment of such disorders. The biotechnology companies are the major consumer of CRISPR gene editing tools.

A plasmid is an extra-chromosomal DNA molecule found in bacteria. Arrayed libraries are used to explore the applications of CRISPR-Cas9 technology into high throughput genome editing screening for functional genomics. Proteins play a fundamental role in the success of the CRISPR technology experiment. The construction of gRNA plays a significant role in obtaining the desired results.

The major market players in the global CRISPR market are:

  • CRISPR Therapeutics AG
  • Sigma-Aldrich
  • Lonza Group AG
  • Thermo Fisher Scientific
  • Novartis International AG

The company profiles cover the analysis of important market players. CRISPR Therapeutics (erstwhile known as Inception Genomics AG) is a biopharmaceutical company based on Basel, Switzerland. They develop gene-based medicines for patients with serious illness using CRISPR-CAS9 gene editing tool. They also develop solutions that translate CRISPR-Cas9, a gene-editing technology, into transformative medicines for lethal diseases. Novartis International AG is a Swiss multinational pharmaceutical organization situated in Basel, Switzerland. Novartis produces medicines such as valsartan (Diovan), diclofenac (Voltaren), carbamazepine (Tegretol), clozapine (Clozaril) and imatinib mesylate (Gleevec/Glivec). Extra specialists incorporate letrozole (Femara), terbinafine (Lamisil), methylphenidate (Ritalin), ciclosporin (Neoral/Sandimmun) and others.

Key findings of the global CRISPR market:

  • Plasmids hold the largest market share in terms of products
  • Industrial biotech is the fastest growing end-user industry
  • Genome editing or genetic engineering is the majorly used application

TABLE OF CONTENTS
  1. RESEARCH SCOPE
    1. STUDY GOALS
    2. SCOPE OF THE MARKET STUDY
    3. WHO WILL FIND THIS REPORT USEFUL?
    4. STUDY AND FORECASTING YEARS
  2. RESEARCH METHODOLOGY
    1. SOURCES OF DATA
      1. SECONDARY DATA
      2. PRIMARY DATA
    2. TOP DOWN APPROACH
    3. BOTTOM-UP APPROACH
    4. DATA TRIANGULATION
  3. EXECUTIVE SUMMARY
    1. MARKET SUMMARY
    2. KEY FINDINGS
      1. PLASMIDS HOLD THE LARGEST MARKET SHARE IN TERMS OF PRODUCTS
      2. INDUSTRIAL BIOTECH IS THE FASTEST GROWING END USER
      3. GENOME EDITING/ GENETIC ENGINEERING IS MAJORLY USED APPLICATION
  4. MARKET DETERMINANTS
    1. MARKET DRIVERS
      1. INCREASING DEMAND FOR DRUG DISCOVERY
      2. LATE PREGNANCIES LEADING TO BIRTH DISORDERS
      3. RISK OF CONGENITAL ANAMOLITIES
      4. AGING GERIATRIC POPULATION
      5. INVESTMENT IN PATH BREAKING RESEARCH TECHNOLOGY
      6. CHANGING LIFESTYLES
      7. PREVALENCE OF GENETIC DISORDERS
      8. INCREASING GENETIC DISEASES
      9. GROWING AWARENESS REGARDING GENE THERAPEUTICS
    2. MARKET RESTRAINTS
      1. POSSIBLE MISUSE OF CRISPR GENE EDITING TOOL
      2. LACK OF AWARENESS
      3. LACK OF HEALTHCARE BUDGETS IN DEVELOPING COUNTRIES
      4. STRINGENT REGULATIONS
    3. MARKET OPPORTUNITIES
      1. GENOME SURGERY TO REWRITE GENETIC DISORDERS
      2. CLINICAL TRIALS IN ASIA
      3. GROWING USAGES OF POTENTIAL APPLICATIONS OF CRISPR TECHNOLOGY
    4. MARKET CHALLENGES
      1. PROTECTION OF PATENT
      2. ALTERNATE TECHNOLOGIES
      3. ETHICAL ISSUES
  5. MARKET BY PRODUCT
    1. DESIGN TOOLS
    2. PLASMIDS
    3. VECTORS
    4. LIBRARY
    5. CONTROL KITS
    6. PROTEINS
      1. CAS 9
      2. CPF1
      3. OTHER PROTEIN
    7. GRNA
    8. OTHER PRODUCTS
  6. MARKET BY END USER
    1. BIOLOGICAL RESEARCH
    2. AGRICULTURAL BIOTECH
    3. INDUSTRIAL BIOTECH
    4. THERAPEUTICS AND DRUG DISCOVERY
  7. MARKET BY APPLICATION
    1. GENOME EDITING/ GENETIC ENGINEERING
      1. GENETICALLY MODIFIED ORGANISMS
      2. AGRICULTURAL BIOTECHNOLOGY
      3. OTHER GENOME EDITING/ GENETIC ENGINEERING
    2. GRNA DATABASE/GENE LIBRARY
    3. CRISPR PLASMID
    4. HUMAN STEM CELLS
    5. CELL LINE ENGINEERING
  8. KEY ANALYTICS
    1. PORTERS 5 FORCE MODEL
      1. THREATS OF NEW ENTRANTS
      2. THREAT OF SUBSTITUTES
      3. BARGAINING POWER OF BUYER
      4. BARGAINING POWER OF SUPPLIER
      5. INTENSITY OF COMPETITIVE RIVALRY
    2. MARKET ETYMOLOGY
    3. SUPPLY CHAIN ANALYSIS
    4. REGULATORY FRAMEWORK
    5. REGULATORY BODIES
    6. VALUE CHAIN ANALYSIS
    7. KEY BUYING CRITERIA
    8. PATENT ANALYSIS
    9. 360 DEGREE ANALYSIS
    10. STRATEGIC RECOMMENDATION AND CONCLUSION
    11. PIPELINE ANALYSIS
  9. GEOGRAPHICAL ANALYSIS
    1. NORTH AMERICA
      1. THE UNITED STATES
      2. CANADA
    2. EUROPE
      1. THE UNITED KINGDOM
      2. FRANCE
      3. GERMANY
      4. SPAIN
      5. ITALY
      6. REST OF EUROPE
    3. ASIA PACIFIC (APAC)
      1. INDIA
      2. CHINA
      3. JAPAN
      4. SOUTH KOREA
      5. AUSTRALIA
      6. REST OF APAC
    4. REST OF THE WORLD
      1. LATIN AMERICA
      2. MIDDLE EAST AND AFRICA
  10. COMPETITIVE ANALYSIS
    1. MARKET SHARE ANALYSIS
    2. COMPANY PROFILE
      1. ADDGENE
      2. APPLIED STEMCELL, INC.
      3. CARIBOU BIOSCIENCES INC.
      4. CELLECTIS BIORESEARCH SAS
      5. CRISPR THERAPEUTICS AG
      6. DIACARTA, INC.
      7. EDIGENE, INC.
      8. EDITAS MEDICINE
      9. GENECOPOEIA, INC.
      10. GENEDATA AG
      11. GENSCRIPT
      12. HORIZON DISCOVERY PLC
      13. INTEGRATED DNA TECHNOLOGIES
      14. INTELLIA THERAPEUTICS INC.
      15. LONZA GROUP AG
      16. NEW ENGLAND BIOLABS INC.
      17. NOVARTIS INTERNATIONAL AG
      18. ORIGENE TECHNOLOGIES INC.
      19. PRECISION BIOSCIENCES
      20. SANGAMO THERAPEUTICS
      21. SIGMA-ALDRICH (MERCK)
      22. THERMO FISHER SCIENTIFIC
      23. TRANSPOSAGEN BIOPHARMACEUTICALS INC.
LIST OF TABLES

TABLE 1 GLOBAL CRISPR MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 2 VARIOUS INITIATIVES AND POLICIES UNDERTAKEN BY THE GOVERNMENT IN HEALTHCARE SECTOR

TABLE 3 RISING PUBLIC HEALTH AND LONG-TERM CARE EXPENDITURE OVER THE NEXT DECADES (%)

TABLE 4 MAJOR CONCERNS RELATED WITH GENETIC ENGINEERING

TABLE 5 GLOBAL CRISPR MARKET BY PRODUCT 2019-2027 ($ MILLIONS)

TABLE 6 TOOLS NAME AND THEIR PROVIDERS

TABLE 7 GLOBAL DESIGN TOOLS MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 8 GLOBAL PLASMIDS MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 9 GLOBAL VECTORS MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 10 GLOBAL LIBRARY MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 11 GLOBAL CONTROL KITS MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 12 GLOBAL PROTEINS MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 13 GLOBAL GRNA MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 14 GLOBAL OTHER PRODUCTS MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 15 GLOBAL CRISPR MARKET BY END USER 2019-2027 ($ MILLIONS)

TABLE 16 GLOBAL BIOLOGICAL RESEARCH MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 17 GLOBAL AGRICULTURAL BIOTECH MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 18 GLOBAL INDUSTRIAL BIOTECH MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 19 GLOBAL THERAPEUTICS AND DRUG DISCOVERY MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 20 GLOBAL CRISPR MARKE BY APPLICATION 2019-2027 ($ MILLIONS)

TABLE 21 GLOBAL GENOME EDITING/ GENETIC ENGINEERING MARKET BY TYPES 2019-2027 ($ MILLIONS)

TABLE 22 GLOBAL GENOME EDITING/ GENETIC ENGINEERING MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 23 BARRIERS TO ENTRY IN THE AGRICULTURAL SEED MARKET

TABLE 24 TRAITS AND TECHNOLOGY HISTORY OF PLANT BIOTECH

TABLE 25 AGRICULTURE BIOTECH TRAITS INDUSTRY

TABLE 26 COMPANY RELATED TO AGRICULTURE BIOTECHNOLOGY INVOLVED IN GENOME EDITING TOOL CRISPR

TABLE 27 AGRICULTURAL BIOTECHNOLOGY COMPANY LICENSING CRISPR PRODUCTS

TABLE 28 KEY COMPETITORS IN THE AGRICULTURAL BIOLOGICALS INDUSTRY

TABLE 29 GLOBAL GRNA DATABASE/GENE LIBRARY MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 30 GLOBAL CRISPR PLASMID MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 31 GLOBAL HUMAN STEM CELLS MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 32 GLOBAL CELL LINE ENGINEERING MARKET BY REGION 2019-2027 ($ MILLIONS)

TABLE 33 GLOBAL CRISPER MARKET BY REGION 2019-2027 ($ MILLION)

TABLE 34 NORTH AMERICA CRISPER MARKET BY COUNTRY 2019-2027 ($ MILLION)

TABLE 35 FUNDS ALLOCATED FOR RESEARCH ACTIVITIES IN BUDGET 2016

TABLE 36 GM CROPS GROWN IN CANADA

TABLE 37 EUROPE CRISPR MARKET BY COUNTRY 2019-2027 ($ MILLION)

TABLE 38 ASIA PACIFIC CRISPR MARKET BY COUNTRY 2019-2027 ($ MILLIONS)

TABLE 39 REST OF WORLD CRISPR MARKET BY COUNTRY 2019-2027 ($ MILLION)

LIST OF FIGURES

FIGURE 1 CAUSES OF DEATHS DURING 2016, WORLDWIDE

FIGURE 2 FATALITIES INCREASING DUE TO LIFESTYLE ORIENTED DISEASES (IN THOUSAND)

FIGURE 3 REASON FOR OUTSOURCING DRUG DISCOVERY PROJECTS

FIGURE 4 GLOBAL CRISPR MARKET BY DESIGN TOOLS 2019-2027 ($ MILLIONS)

FIGURE 5 GLOBAL CRISPR MARKET BY PLASMIDS 2019-2027 ($ MILLIONS)

FIGURE 6 GLOBAL CRISPR MARKET BY VECTORS 2019-2027 ($ MILLIONS)

FIGURE 7 GLOBAL CRISPR MARKET BY LIBRARY 2019-2027 ($ MILLIONS)

FIGURE 8 GLOBAL CRISPR MARKET BY CONTROL KITS 2019-2027 ($ MILLIONS)

FIGURE 9 GLOBAL CRISPR MARKET BY PROTEINS 2019-2027 ($ MILLIONS)

FIGURE 10 GLOBAL PROTEINS MARKET BY CAS 9 2019-2027 ($ MILLIONS)

FIGURE 11 GLOBAL PROTEINS MARKET BY CPF1 2019-2027 ($ MILLIONS)

FIGURE 12 GLOBAL PROTEINS MARKET BY OTHER PROTEIN 2019-2027 ($ MILLIONS)

FIGURE 13 GLOBAL CRISPR MARKET BY GRNA 2019-2027 ($ MILLIONS)

FIGURE 14 GLOBAL CRISPR MARKET BY OTHER PRODUCTS 2019-2027 ($ MILLIONS)

FIGURE 15 GLOBAL CRISPR MARKET BY BIOLOGICAL RESEARCH 2019-2027 ($ MILLION)

FIGURE 16 GLOBAL CRISPR MARKET BY AGRICULTURAL BIOTECH 2019-2027 ($ MILLION)

FIGURE 17 GLOBAL CRISPR MARKET BY INDUSTRIAL BIOTECH2019-2027 ($ MILLION)

FIGURE 18 GLOBAL CRISPR MARKET BY THERAPEUTICS AND DRUG DISCOVERY 2019-2027 ($ MILLION)

FIGURE 19 GLOBAL CRISPR MARKET BY GENOME EDITING/ GENETIC ENGINEERING 2019-2027 ($ MILLIONS)

FIGURE 20 GLOBAL GENOME EDITING/ GENETIC ENGINEERING MARKET BY GENETICALLY MODIFIED ORGANISMS/CROPS 2019-2027 ($ MILLIONS)

FIGURE 21 GLOBAL GENOME EDITING/ GENETIC ENGINEERING MARKET BY AGRICULTURAL BIOTECHNOLOGY 2019-2027 ($ MILLIONS)

FIGURE 22 GLOBAL GENOME EDITING/ GENETIC ENGINEERING MARKET BY OTHER GENOME EDITING/ GENETIC ENGINEERING 2019-2027 ($ MILLIONS)

FIGURE 23 GLOBAL CRISPR MARKET BY GRNA DATABASE/GENE LIBRARY 2019-2027 ($ MILLIONS)

FIGURE 24 GLOBAL CRISPR MARKET BY CRISPR PLASMID 2019-2027 ($ MILLIONS)

FIGURE 25 GLOBAL CRISPR MARKET BY HUMAN STEM CELLS 2019-2027 ($ MILLIONS)

FIGURE 26 GLOBAL CRISPR MARKET BY CELL LINE ENGINEERING 2019-2027 ($ MILLIONS)

FIGURE 27 TIMELINE OF GLOBAL CRISPR MARKET

FIGURE 28 VALUE CHAIN ANALYSIS

FIGURE 29 GLOBAL CRISPR MARKET SHARE BY REGION 2018 AND 2027 (%)

FIGURE 30 NORTH AMERICA CRISPER MARKET 2019-2027 ($ MILLION)

FIGURE 31 ADOPTION OF GMO CROPS IN THE U.S. IN 2018 (%)

FIGURE 32 THE UNITED STATES CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 33 REASONS FOR ADOPTING GENETICALLY ENGINEERED CROP (BT COTTON)

FIGURE 34 GM CROPS GROWN IN CANADA

FIGURE 35 CANADA CRISPER MARKET 2019-2027 ($ MILLION)

FIGURE 36 EUROPE CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 37 THE UNITED KINGDOM CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 38 FRANCE CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 39 GERMANY CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 40 SPAIN CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 41 ITALY CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 42 REST OF EUROPE CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 43 INDIA CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 44 CHINA CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 45 JAPAN CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 46 SOUTH KOREA CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 47 AUSTRALIA CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 48 REST OF APAC CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 49 LATIN AMERICA CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 50 MIDDLE EAST AND AFRICA CRISPR MARKET 2019-2027 ($ MILLION)

FIGURE 51 CRISPR MARKET COMPANIES SHARE 2018 (%)

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